People
PhD student at Leinbiz-HKI, department of infection immunology. My project name is "GSDME function and regulation in T-cells". The goal of my project is to investigate the function and regulation of a recently found pore-forming protein GSDME in T-cells, how it affects effector functions of T-cells and what is the physiological and clinical relevance of this structure.
Projects: Not specified
Institutions: Not specified
Ich bin Innenarchitektin mit einer Leidenschaft für die Gestaltung stilvoller und funktionaler Lebensräume. Ich lasse mich von der Schönheit der Natur inspirieren. Außerdem bin ich mehrsprachig und spreche fließend Englisch, Deutsch und Niederländisch. Dies ermöglicht mir eine effektive Kommunikation mit Kunden aus verschiedenen Kulturen und mit unterschiedlichem Hintergrund. Ich bin in der Lage, einen Sinn für Vielfalt in jeden Entwurf einzubringen. So kann ich etwas wirklich Einzigartiges
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Projects: Not specified
Institutions: Not specified
Hoi, mijn naam is Karlijn en ik ben gek op alles wat met interieurdesign van zowel de woonkamer als de slaapkamer te maken heeft. Het is mijn passie! Ik schrijf regelmatig artikelen over dit onderwerp, omdat ik anderen wil helpen om mooie ruimtes te creëren en een goede nachtrust te krijgen.Mijn hoop is dat ik door het delen van mijn kennis een verschil kan maken in het leven van mensen.
PhD Scholar at University of Delhi, New Delhi, India. My research interest revolves around Multi-omic investigation of resistance mechanism in fungal pathogens.
Projects: FungiNet total
Institutions: Friedrich-Schiller-University
Automated analysis of microscopic image data of host-pathogen interaction
Projects: C7
Institutions: Julius Maximilians University Würzburg, Institute for Molecular Infection Biology
Projects: A7
Institutions: Friedrich-Schiller-University
Projects: A1
Institutions: University Hospital Jena
Principal investigator in B1.
Full professor in bioinformatics at FSU Jena
Projects: A4 (E)
Institutions: Julius Maximilians University Würzburg, Department of Internal Medicine II
Projects: A1, A2, A3, A4 (E), A5, A6, B1, B2, B4, B5, C2, C1, C3, C4 (E), C5, C6 (E), FungiNet A - Aspergillus projects, FungiNet B - Bioinformatics projects, FungiNet C - Candida projects, FungiNet total, INF, Z1, Z2, B3 (E), A7, A8, C7
Institutions: Leibniz-Institute for Natural Product Research and Infection Biology Hans Knöll Institute (HKI)

Spatiotemporal Modeling and Simulation of Fungal Infection Processes
Head of the subgroup Stress and Immunoproteomics of the Department of Molecular and Applied Microbiology Department at the HKI
Projects: FungiNet total, INF, A1, A2, A3, A4 (E), A5, A6, B1, B2, B3 (E), B4, B5, C1, C2, C3, C4 (E), C5, C6 (E), FungiNet A - Aspergillus projects, FungiNet B - Bioinformatics projects, FungiNet C - Candida projects, Z1, Z2
Institutions: Leibniz-Institute for Natural Product Research and Infection Biology Hans Knöll Institute (HKI)
Projects: FungiNet total, INF, A1, A2, A3, A4 (E), A5, A6, B1, B3 (E), B4, B5, C1, C2, C3, C4 (E), C5, C6 (E), Z1, Z2, FungiNet A - Aspergillus projects, FungiNet B - Bioinformatics projects, FungiNet C - Candida projects, B2
Institutions: Leibniz-Institute for Natural Product Research and Infection Biology Hans Knöll Institute (HKI)

Projects: A2
Institutions: Julius Maximilians University Würzburg, Department of Internal Medicine II
I am responisble for the spatial proteomics part in Z2. We provide a proteomic platform to study spatial changes of the proteome during host-fungal pathogen interaction using MALDI-MS Imaging and Lasermicrodissection. As type of biological sample we can work with cryo and formalin fixed tissue, as well as cell cultures and lysed sample solutions.
Please get into contact with me if you are interested in MALDI-MS Imaging for your research project.
Project leader C2
Projects: FungiNet A - Aspergillus projects, FungiNet B - Bioinformatics projects, FungiNet C - Candida projects, FungiNet total, Z1
Institutions: Friedrich-Schiller-University, Friedrich Schiller University Jena, Jena School for Microbial Communication, Friedrich Schiller University Jena, Institute of Microbiology, Dept. of Microbiology and Molecular Biology, Leibniz-Institute for Natural Product Research and Infection Biology Hans Knöll Institute (HKI)
Management SFB FungiNet
Projects: A3
Institutions: Julius Maximilians University Würzburg, Biocenter, Department of Biotechnology and Biophysics
Projects: A2, FungiNet total
Institutions: Julius Maximilians University Würzburg, Department of Internal Medicine II
Doktorandin
Rolle von CD56 in der Interaktion von Natürlichen Killerzellen mit Aspergillus fumigatus
Interaktionsanalysen von humanen Dendritischen Zellen und natürlichen Killerzellen bei der Konfrontation mit Aspergillus fumigatus
Projects: FungiNet A - Aspergillus projects, FungiNet B - Bioinformatics projects, FungiNet C - Candida projects, FungiNet total, A1, Z1
Institutions: Friedrich Schiller University Jena, Institute of Microbiology, Dept. of Microbiology and Molecular Biology, Friedrich Schiller University Jena, Jena School for Microbial Communication, Leibniz-Institute for Natural Product Research and Infection Biology Hans Knöll Institute (HKI)
Projects: INF, FungiNet total, A1, A2, FungiNet A - Aspergillus projects, A3, A4 (E), A5, A6, FungiNet C - Candida projects, C1, C2, C3, C4 (E), C5, C6 (E), FungiNet B - Bioinformatics projects, B3 (E)
Institutions: HITS Heidelberger Institut für Theoretische Studien gGmbH
Within the de.NBI project my functions in the de.NBI-SysBio node comprise content curation, requirements elicitation, and community engagement for the users of biochemical reaction kinetics database SABIO-RK as well as of the data management platform SEEK.
Bioprocess data analysis (data mining)
Transcriptomics and proteomics data analysis and modelling
Gene Regulatory Network inference (Reverse engineering)
Decision making support systems in diagnostics, therapy and biotechnology
Projects: INF
Institutions: HITS Heidelberger Institut für Theoretische Studien gGmbH
Projects: INF
Institutions: BioControl Jena GmbH
Projects: Z2, FungiNet total
Institutions: University Hospital Jena, Friedrich-Schiller-University

I study the analysis of high-throughput transcriptom and genome data.
For transcritom data (RNA-Seq, microarrays), I perform preprocessing and statistics to identify differentially expressed genes, as well as their functional analysis. My main focus is the analysis of transcriptom data
from human fungal pathogens in infection related conditions (f.e. nutrient limitation) as well as during the interaction with the host (dual RNA-seq).
Experimental data is used to set up mathematical models for
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Projects: C1
Institutions: Julius Maximilians University Würzburg, Institute for Molecular Infection Biology
Projects: A4 (E)
Institutions: Julius Maximilians University Würzburg, Department of Internal Medicine II
Projects: B4
Institutions: Leibniz-Institute for Natural Product Research and Infection Biology Hans Knöll Institute (HKI)
Projects: Not specified
Institutions: Not specified
The following bullet points characterise my scientific interests and research:
- Metabolic physiology of fungi during host infection
- Biochemical characterisation of metabolic pathways (enzyme purification and characterisation)
- Development of infection models
- Generation of fungal reporter strains
- In vivo imaging of the infection process
- Secondary metabolites from Aspergillus terreus (gene regulation, product formation, biological activity)
Projects: C2, FungiNet total, FungiNet C - Candida projects
Institutions: Friedrich-Schiller-University
Institutions: BioControl Jena GmbH
Projects: C1
Institutions: Julius Maximilians University Würzburg, Institute for Molecular Infection Biology
Projects: A3
Institutions: Julius Maximilians University Würzburg, Department of Internal Medicine II
Projects: B4
Institutions: Leibniz-Institute for Natural Product Research and Infection Biology Hans Knöll Institute (HKI)
Projects: A3
Institutions: Julius Maximilians University Würzburg, Biocenter, Department of Biotechnology and Biophysics
Projects: C5
Institutions: Leibniz-Institute for Natural Product Research and Infection Biology Hans Knöll Institute (HKI)
Name
Prof. Dr. Thomas Dandekar
Position Professor and Chairman
Affiliation
Dept. of bioinformatics,
Biocenter
University of Würzburg
Am Hubland
97074 Würzburg
Phone 0931-318-4551
dandekar@biozentrum.uni-wuerzburg.de
Born 23.07.1960
Career 1979-1986 Studies in medicine at the Ludwig Maximilians University of Munich
1982-1986 MD, Max Planck Inst. of Psychiatry, Dept. Neuropharmacology, Martinsried
1987-1988 Post-Doc, Institute Pasteur, Paris
1988- now Scientist at the European Molecular Biology
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Project C1