Immunomodulatory functions of ITAM- and ITIM-coupled receptors (C-type lectins/CTLs and carcinoembryonic antigen-related cell adhesion molecules/CEACAMs) for C. albicans -induced immune responses
SEEK ID: https://funginet.hki-jena.de/projects/23
Public web page: http://www.funginet.de/project-a5.html
Organisms: Aspergillus fumigatus, Candida albicans, Homo sapiens
INF PALs: No PALs for this Project
Project created: 21st Jul 2015
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Projects: FungiNet total, INF, A1, A2, A3, A4 (E), A5, A6, B1, B3 (E), B4, B5, C1, C2, C3, C4 (E), C5, C6 (E), Z1, Z2, FungiNet A - Aspergillus projects, FungiNet B - Bioinformatics projects, FungiNet C - Candida projects, B2
Institutions: Leibniz-Institute for Natural Product Research and Infection Biology Hans Knöll Institute (HKI)
https://orcid.org/0000-0001-6106-724XProjects: A5, FungiNet A - Aspergillus projects, FungiNet total
Institutions: Friedrich Schiller University Jena, Center for Innovation Competence (ZIK) Septomics
https://orcid.org/0000-0001-7389-6862Expertise: cell surface receptors, CEACAM family receptors, Cell biology, protein biochemistry, protein-protein interaction, signaling mechanisms
Tools: 2D and 3D cell culture, migration and invasion assays, Immunological techniques, Biochemistry and protein analysis, Cytometry and fluorescent microscopy
Projects: INF, FungiNet total, A1, A2, FungiNet A - Aspergillus projects, A3, A4 (E), A5, A6, FungiNet C - Candida projects, C1, C2, C3, C4 (E), C5, C6 (E), FungiNet B - Bioinformatics projects, B3 (E)
Institutions: HITS Heidelberger Institut für Theoretische Studien gGmbH
Expertise: Data Management, Data Curation, Biochemistry, Molecular Biology, Microbiology, Phytopathology
Within the de.NBI project my functions in the de.NBI-SysBio node comprise content curation, requirements elicitation, and community engagement for the users of biochemical reaction kinetics database SABIO-RK as well as of the data management platform SEEK.
Projects: A1, A2, A3, A4 (E), A5, A6, B1, B2, B4, B5, C2, C1, C3, C4 (E), C5, C6 (E), FungiNet A - Aspergillus projects, FungiNet B - Bioinformatics projects, FungiNet C - Candida projects, FungiNet total, INF, Z1, Z2, B3 (E), A7, A8, C7
Institutions: Leibniz-Institute for Natural Product Research and Infection Biology Hans Knöll Institute (HKI)
https://orcid.org/0000-0003-3862-6546Expertise: Systems Biology, Bioinformatics, Metabolic networks
Tools: Matlab, R, Python, Copasi, LaTeX, Systems biological modelling, Transcriptomics
The yeast Candida albicans and the filamentous fungus Aspergillus fumigatus are by far the most important causes of life-threatening invasive mycoses in Europe. Despite the increasing incidence of these infections, the current diagnosis is still difficult and often too late, and options for therapies are limited. Moreover, A. fumigatus and C. albicans have developed multiple sophisticated, specific and unique pathogenicity mechanisms. Many of these mechanisms are not well understood. Research on ...
Projects: FungiNet total, FungiNet A - Aspergillus projects, FungiNet B - Bioinformatics projects, FungiNet C - Candida projects, INF, A1, A2, A3, A4 (E), A5, B1, B2, B3 (E), B4, C1, C2, C3, C4 (E), C5, C6 (E), Z2, Z1, B5, A6, A7, A8, C7
Web page: http://www.funginet.de/home.html
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Authors: M. H. Mirhakkak, S. Schauble, T. E. Klassert, S. Brunke, P. Brandt, D. Loos, R. V. Uribe, F. Senne de Oliveira Lino, Y. Ni, S. Vylkova, H. Slevogt, B. Hube, G. J. Weiss, M. O. A. Sommer, G. Panagiotou
Date Published: 15th Dec 2020
Publication Type: Not specified
PubMed ID: 33323978
Citation: ISME J. 2020 Dec 15. pii: 10.1038/s41396-020-00848-z. doi: 10.1038/s41396-020-00848-z.
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Publication Type: Not specified
PubMed ID: 33043780
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Publication Type: Not specified
PubMed ID: 32583550
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Authors: E. Klaile, M. M. Muller, C. Zubiria-Barrera, S. Brehme, T. E. Klassert, M. Stock, A. Durotin, T. D. Nguyen, S. Feer, B. B. Singer, P. F. Zipfel, S. Rudolphi, I. D. Jacobsen, H. Slevogt
Date Published: 19th Dec 2019
Publication Type: Not specified
PubMed ID: 31849868
Citation: Front Microbiol. 2019 Nov 26;10:2703. doi: 10.3389/fmicb.2019.02703. eCollection 2019.
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Authors: S. Goyal, J. C. Castrillon-Betancur, E. Klaile, H. Slevogt
Date Published: 20th Jun 2018
Publication Type: Not specified
PubMed ID: 29915598
Citation: Front Immunol. 2018 Jun 4;9:1261. doi: 10.3389/fimmu.2018.01261. eCollection 2018.