B2
OverviewInteraction networks of signalling molecules and pathways between the pathogenic fungi Aspergillus fumigatus and Candida albicans and their human host
SEEK ID: https://funginet.hki-jena.de/projects/25
Public web page: http://www.funginet.de/project-b2.html
Organisms: Aspergillus fumigatus, Candida albicans
INF PALs: No PALs for this Project
Project created: 21st Jul 2015
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Name Prof. Dr. Thomas Dandekar Position Professor and Chairman Affiliation Dept. of bioinformatics, Biocenter University of Würzburg Am Hubland 97074 Würzburg Phone 0931-318-4551 dandekar@biozentrum.uni-wuerzburg.de Born 23.07.1960
Career 1979-1986 Studies in medicine at the Ludwig Maximilians University of Munich 1982-1986 MD, Max Planck Inst. of Psychiatry, Dept. Neuropharmacology, Martinsried 1987-1988 Post-Doc, Institute Pasteur, Paris 1988- now Scientist at the European Molecular Biology ...
https://orcid.org/0000-0002-9415-2317
The yeast Candida albicans and the filamentous fungus Aspergillus fumigatus are by far the most important causes of life-threatening invasive mycoses in Europe. Despite the increasing incidence of these infections, the current diagnosis is still difficult and often too late, and options for therapies are limited. Moreover, A. fumigatus and C. albicans have developed multiple sophisticated, specific and unique pathogenicity mechanisms. Many of these mechanisms are not well understood. Research on ...
Projects: FungiNet total, FungiNet A - Aspergillus projects, FungiNet B - Bioinformatics projects, FungiNet C - Candida projects, INF, A1, A2, A3, A4 (E), A5, B1, B2, B3 (E), B4, C1, C2, C3, C4 (E), C5, C6 (E), Z2, Z1, B5, A6, A7, A8, C7
Web page: http://www.funginet.de/home.html
Dynamic optimization model to study control points in metabolic pathways to identify general strategies behind pathway regulation. Toxic intermediates determine which enzyme control pathway flux and prevent their accumulation. Therefore those enzymes are drug targets since deregulation leads to self-poisoning of pathogens.
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Authors: J. Balkenhol, K. V. Kaltdorf, E. Mammadova-Bach, A. Braun, B. Nieswandt, M. Dittrich, T. Dandekar
Date Published: 22nd Dec 2020
Publication Type: Not specified
Abstract (Expand)
Authors: L. Urban, C. W. Remmele, M. Dittrich, R. F. Schwarz, T. Muller
Date Published: 24th Feb 2020
Publication Type: Not specified
Abstract (Expand)
Authors: M. Dittrich, H. M. Mueller, H. Bauer, M. Peirats-Llobet, P. L. Rodriguez, C. M. Geilfus, S. C. Carpentier, K. A. S. Al Rasheid, H. Kollist, E. Merilo, J. Herrmann, T. Muller, P. Ache, A. M. Hetherington, R. Hedrich
Date Published: 28th Aug 2019
Publication Type: Not specified
Abstract (Expand)
Authors: T. Breitenbach, C. Liang, N. Beyersdorf, T. Dandekar
Date Published: 17th Jul 2019
Publication Type: Not specified
Abstract (Expand)
Authors: L. Page, P. Weis, T. Muller, M. Dittrich, M. Lazariotou, M. Dragan, A. M. Waaga-Gasser, J. Helm, T. Dandekar, H. Einsele, J. Loffler, A. J. Ullmann, S. Wurster
Date Published: 12th Sep 2018
Publication Type: Not specified
