- Projects (2)
- Institutions (1)
- Investigations (14+9)
- Studies (42+20)
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- Publications (4)
In project Z2 a sophisticated proteome analysis platform will be provided based on 2D-gel electrophoresis (2D-GE), MALDI-TOF and LC-MS/MS techniques to specific A and Cprojects.
Integrated database for experimental data
Within the Collaborative Research Center / Transregio 124 “Pathogenic fungi and their human host: Networks of Interaction – FungiNet”, the INF project is responsible to analyse and share OMICS data. Databases help to foster the collaboration within FungiNet as an important point of the Collaborative Research Center. Therefore, we set-up two databases:
a) SEEK is a web-based platform to find, share and exchange unstructured data and knowledge, such as
P Hortschansky, M Eisendle, Q Al-Abdallah, A D Schmidt, S Bergmann, M Thön, O Kniemeyer, B Abt, B Seeber, E R Werner, M Kato, A A Brakhage and H Haas. Interaction of HapX with the CCAAT-binding complex-a novel mechanism of gene regulation by iron. EMBO J. 2007 Jul 11;26(13):3157-68. Epub 2007 Jun 14
Wartenberg D, Vödisch M, Kniemeyer O, Albrecht-Eckardt D, Scherlach K, Winkler R, Weide M, Brakhage AA. Proteome analysis of the farnesol-induced stress response in Aspergillus nidulans-The role of a putative dehydrin. J Proteomics. 2012 May 23.
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D Albrecht, R Guthke, A A Brakhage, O Kniemeyer. Integrative analysis of the heat shock response in Aspergillus fumigatus. BMC Genomics. 2010 Jan 15;11:32.
Find corresponding transcriptomic data at ArrayExpress: E-MEXP-332
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Dirk Wartenberg, Katrin Lapp, Ilse D. Jacobsen, Hans-Martin Dahse, Olaf Kniemeyer, Thorsten Heinekamp, Axel A. Brakhage
Leibniz Institute for Natural Product Research and Infection Biology-Hans-Knoell-Institute (HKI), Jena, Germany. Secretome analysis of Aspergillus fumigatus reveals Asp-hemolysin as a major secreted protein. Int J Med Microbiol. 2011, Nov;301(7):602-11
Teutschbein J, Simon S, Lother J, Springer J, Hortschansky P, Morton CO, Löffler J, Einsele H, Conneally E, Rogers TR, Guthke R, Brakhage AA, Kniemeyer O. Proteomic profiling of serological responses to Aspergillus fumigatus antigens in patients with invasive aspergillosis. J Proteome Res 2016 Mar 24
Aspergillus nidulans R21 was grown over night in AMM at 37°C and 200 rpm. The culture was treated with 50 µM farnesol or the same volume of ethanol without farnesol as control. The culture was harvested after 3 hours of further incubation.
Authors: S. Ruben, E. Garbe, Selene Mogavero, Daniela Albrecht-Eckardt, D. Hellwig, A. Hader, Thomas Krüger, K. Gerth, Ilse Jacobsen, O. Elshafee, S. Brunke, Kerstin Hünniger, Olaf Kniemeyer, Axel Brakhage, Joachim Morschhäuser, Bernhard Hube, Slavena Vylkova, Oliver Kurzai, R. Martin
Date Published: 28th Apr 2020
PubMed ID: 32345638
Citation: mBio. 2020 Apr 28;11(2). pii: mBio.00206-20. doi: 10.1128/mBio.00206-20.
Date Published: 19th May 2016
Journal: Front Microbiol
PubMed ID: 27242763
Date Published: 12th Jan 2016
Journal: Cell Microbiol
PubMed ID: 26752615
Date Published: 14th Mar 2013
Journal: PLoS One
PubMed ID: 23516516