Julius Maximilians University Würzburg, Department of Internal Medicine II

The yeast Candida albicans and the filamentous fungus Aspergillus fumigatus are by far the most important causes of life-threatening invasive mycoses in Europe. Despite the increasing incidence of these infections, the current diagnosis is still difficult and often too late, and options for therapies are limited. Moreover, A. fumigatus and C. albicans have developed multiple sophisticated, specific and unique pathogenicity mechanisms. Many of these mechanisms are not well understood. Research on ...

Interaction of Aspergillus fumigatus with human natural killer cells, dendritic cells and human alveolar epithelia

In vivo analysis of temporal and spatial disease progression and immune cell recruitment during invasive Aspergillus fumigatus and Candida albicans infections