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Proteome Analysis Reveals the Conidial Surface Protein CcpA Essential for Virulence of the Pathogenic Fungus Aspergillus fumigatus.

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Abstract (Expand)

Aspergillus fumigatus is a common airborne fungal pathogen of humans and a significant source of mortality in immunocompromised individuals. Here, we provide the most extensive cell wall proteome ...

Authors: Thorsten Heinekamp, Thomas Krüger, Esther Weiß, Kerstin Hünniger, Jürgen Löffler, Oliver Kurzai, Hermann Einsele, Olaf Kniemeyer, Axel Brakhage, Voltersen V.,Blango M. G.,Herrmann S.,Schmidt F.,Strassburger M.,Bacher P.,Lother J.,Liu H.,Hortschansky P.,Scheffold A.,Krappmann S.,Nietzsche S.,Filler S. G.,Reichard U.

Date Published: No date defined

Journal: MBio

PubMed ID: 30279286

Citation: MBio. 2018 Oct 2;9(5). pii: mBio.01557-18. doi: 10.1128/mBio.01557-18.

Created: 15th Jan 2019 at 12:50

The Candida albicans Histone Acetyltransferase Hat1 Regulates Stress Resistance and Virulence via Distinct Chromatin Assembly Pathways.

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Abstract (Expand)

Human fungal pathogens like Candida albicans respond to host immune surveillance by rapidly adapting their transcriptional programs. Chromatin assembly factors are involved in the regulation of stress ...

Author: Tscherner M.,Zwolanek F.,Jenull S.,Sedlazeck F. J.,Petryshyn A.,Frohner I. E.,Mavrianos J.,Chauhan N.,von Haeseler A.,Kuchler K.

Date Published: No date defined

Journal: PLoS Pathog

PubMed ID: 26473952

Citation: PLoS Pathog. 2015 Oct 16;11(10):e1005218. doi: 10.1371/journal.ppat.1005218. eCollection 2015 Oct.

Created: 25th Jul 2018 at 10:20

Dual-species transcriptional profiling during systemic candidiasis reveals organ-specific host-pathogen interactions.

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Abstract (Expand)

Candida albicans is a common cause of life-threatening fungal bloodstream infections. In the murine model of systemic candidiasis, the kidney is the primary target organ while the fungal load declines ...

Authors: Michael Bauer, Jörg Linde, Ilse Jacobsen, Hebecker B.,Vlaic S.,Conrad T.,Brunke S.,Kapitan M.,Hube B.

Date Published: No date defined

Journal: Sci Rep

PubMed ID: 27808111

Citation: Sci Rep. 2016 Nov 3;6:36055. doi: 10.1038/srep36055.

Created: 28th Feb 2018 at 11:20

Identification and functional characterization of Rca1, a transcription factor involved in both antifungal susceptibility and host response in Candida albicans.

FungiNet C - Candida projects

Abstract (Expand)

The identification of novel transcription factors associated with antifungal response may allow the discovery of fungus-specific targets for new therapeutic strategies. A collection of 241 Candida ...

Author: Vandeputte P.,Pradervand S.,Ischer F.,Coste A. T.,Ferrari S.,Harshman K.,Sanglard D.

Date Published: No date defined

Journal: Eukaryot Cell

PubMed ID: 22581526

Citation: Eukaryot Cell. 2012 Jul;11(7):916-31. doi: 10.1128/EC.00134-12. Epub 2012 May 11.

Created: 17th Jan 2018 at 09:34

RNAseq analysis of Aspergillus fumigatus in blood reveals a just wait and see resting stage behavior.

FungiNet A - Aspergillus projects

Abstract (Expand)

BACKGROUND: Invasive aspergillosis is started after germination of Aspergillus fumigatus conidia that are inhaled by susceptible individuals. Fungal hyphae can grow in the lung through the epithelial ...

Author: Irmer H.,Tarazona S.,Sasse C.,Olbermann P.,Loeffler J.,Krappmann S.,Conesa A.,Braus G. H.

Date Published: 28th Aug 2015

Journal: BMC Genomics

PubMed ID: 26311470

Citation: BMC Genomics. 2015 Aug 27;16:640. doi: 10.1186/s12864-015-1853-1.

Created: 15th Nov 2017 at 12:17

Function and Regulation of Cph2 in Candida albicans.

FungiNet C - Candida projects

Abstract (Expand)

Candida albicans is associated with humans as both a harmless commensal organism and a pathogen. Cph2 is a transcription factor whose DNA binding domain is similar to that of mammalian sterol response ...

Author: Lane S.,Di Lena P.,Tormanen K.,Baldi P.,Liu H.

Date Published: 6th Sep 2015

Journal: Eukaryot Cell

PubMed ID: 26342020

Citation: Eukaryot Cell. 2015 Nov;14(11):1114-26. doi: 10.1128/EC.00102-15. Epub 2015 Sep 4.

Created: 15th Nov 2017 at 12:14

pH Regulates White-Opaque Switching and Sexual Mating in Candida albicans.

FungiNet C - Candida projects

Abstract (Expand)

As a successful commensal and pathogen of humans, Candida albicans encounters a wide range of environmental conditions. Among them, ambient pH, which changes frequently and affects many biological ...

Author: Sun Y.,Cao C.,Jia W.,Tao L.,Guan G.,Huang G.

Date Published: 6th Sep 2015

Journal: Eukaryot Cell

PubMed ID: 26342021

Citation: Eukaryot Cell. 2015 Nov;14(11):1127-34. doi: 10.1128/EC.00123-15. Epub 2015 Sep 4.

Created: 15th Nov 2017 at 12:12

White cells facilitate opposite- and same-sex mating of opaque cells in Candida albicans.

FungiNet C - Candida projects

Abstract (Expand)

Modes of sexual reproduction in eukaryotic organisms are extremely diverse. The human fungal pathogen Candida albicans undergoes a phenotypic switch from the white to the opaque phase in order to become ...

Author: Tao L.,Cao C.,Liang W.,Guan G.,Zhang Q.,Nobile C. J.,Huang G.

Date Published: 21st Oct 2014

Journal: PLoS Genet

PubMed ID: 25329547

Citation: PLoS Genet. 2014 Oct 16;10(10):e1004737. doi: 10.1371/journal.pgen.1004737. eCollection 2014 Oct.

Created: 15th Nov 2017 at 12:11

Role of Candida albicans Tem1 in mitotic exit and cytokinesis.

FungiNet C - Candida projects

Abstract (Expand)

Candida albicans demonstrates three main growth morphologies: yeast, pseudohyphal and true hyphal forms. Cell separation is distinct in these morphological forms and the process of separation is closely ...

Author: Milne S. W.,Cheetham J.,Lloyd D.,Shaw S.,Moore K.,Paszkiewicz K. H.,Aves S. J.,Bates S.

Date Published: 29th Jun 2014

Journal: Fungal Genet Biol

PubMed ID: 24973462

Citation: Fungal Genet Biol. 2014 Aug;69:84-95. doi: 10.1016/j.fgb.2014.06.007. Epub 2014 Jun 25.

Created: 15th Nov 2017 at 12:09

A histone deacetylase adjusts transcription kinetics at coding sequences during Candida albicans morphogenesis.

FungiNet C - Candida projects

Abstract (Expand)

Despite their classical role as transcriptional repressors, several histone deacetylases, including the baker's yeast Set3/Hos2 complex (Set3C), facilitate gene expression. In the dimorphic human ...

Author: Hnisz D.,Bardet A. F.,Nobile C. J.,Petryshyn A.,Glaser W.,Schock U.,Stark A.,Kuchler K.

Date Published: 14th Dec 2012

Journal: PLoS Genet

PubMed ID: 23236295

Citation: PLoS Genet. 2012;8(12):e1003118. doi: 10.1371/journal.pgen.1003118. Epub 2012 Dec 6.

Created: 15th Nov 2017 at 12:00

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