Publications

Abstract (Expand)

Aspergillus fumigatus is a common airborne fungal pathogen of humans and a significant source of mortality in immunocompromised individuals. Here, we provide the most extensive cell wall proteome ...

Authors: Thorsten Heinekamp, Thomas Krüger, Esther Weiß, Kerstin Hünniger, Jürgen Löffler, Oliver Kurzai, Hermann Einsele, Olaf Kniemeyer, Axel Brakhage, Voltersen V.,Blango M. G.,Herrmann S.,Schmidt F.,Strassburger M.,Bacher P.,Lother J.,Liu H.,Hortschansky P.,Scheffold A.,Krappmann S.,Nietzsche S.,Filler S. G.,Reichard U.

Date Published: No date defined

Journal: MBio

Abstract (Expand)

Human fungal pathogens like Candida albicans respond to host immune surveillance by rapidly adapting their transcriptional programs. Chromatin assembly factors are involved in the regulation of stress ...

Author: Tscherner M.,Zwolanek F.,Jenull S.,Sedlazeck F. J.,Petryshyn A.,Frohner I. E.,Mavrianos J.,Chauhan N.,von Haeseler A.,Kuchler K.

Date Published: No date defined

Journal: PLoS Pathog

Abstract (Expand)

Candida albicans is a common cause of life-threatening fungal bloodstream infections. In the murine model of systemic candidiasis, the kidney is the primary target organ while the fungal load declines ...

Authors: Michael Bauer, Jörg Linde, Ilse Jacobsen, Hebecker B.,Vlaic S.,Conrad T.,Brunke S.,Kapitan M.,Hube B.

Date Published: No date defined

Journal: Sci Rep

Abstract (Expand)

The identification of novel transcription factors associated with antifungal response may allow the discovery of fungus-specific targets for new therapeutic strategies. A collection of 241 Candida ...

Author: Vandeputte P.,Pradervand S.,Ischer F.,Coste A. T.,Ferrari S.,Harshman K.,Sanglard D.

Date Published: No date defined

Journal: Eukaryot Cell

Abstract (Expand)

BACKGROUND: Invasive aspergillosis is started after germination of Aspergillus fumigatus conidia that are inhaled by susceptible individuals. Fungal hyphae can grow in the lung through the epithelial ...

Author: Irmer H.,Tarazona S.,Sasse C.,Olbermann P.,Loeffler J.,Krappmann S.,Conesa A.,Braus G. H.

Date Published: 28th Aug 2015

Journal: BMC Genomics

Abstract (Expand)

Candida albicans is associated with humans as both a harmless commensal organism and a pathogen. Cph2 is a transcription factor whose DNA binding domain is similar to that of mammalian sterol response ...

Author: Lane S.,Di Lena P.,Tormanen K.,Baldi P.,Liu H.

Date Published: 6th Sep 2015

Journal: Eukaryot Cell

Abstract (Expand)

As a successful commensal and pathogen of humans, Candida albicans encounters a wide range of environmental conditions. Among them, ambient pH, which changes frequently and affects many biological ...

Author: Sun Y.,Cao C.,Jia W.,Tao L.,Guan G.,Huang G.

Date Published: 6th Sep 2015

Journal: Eukaryot Cell

Abstract (Expand)

Modes of sexual reproduction in eukaryotic organisms are extremely diverse. The human fungal pathogen Candida albicans undergoes a phenotypic switch from the white to the opaque phase in order to become ...

Author: Tao L.,Cao C.,Liang W.,Guan G.,Zhang Q.,Nobile C. J.,Huang G.

Date Published: 21st Oct 2014

Journal: PLoS Genet

Abstract (Expand)

Candida albicans demonstrates three main growth morphologies: yeast, pseudohyphal and true hyphal forms. Cell separation is distinct in these morphological forms and the process of separation is closely ...

Author: Milne S. W.,Cheetham J.,Lloyd D.,Shaw S.,Moore K.,Paszkiewicz K. H.,Aves S. J.,Bates S.

Date Published: 29th Jun 2014

Journal: Fungal Genet Biol

Abstract (Expand)

Despite their classical role as transcriptional repressors, several histone deacetylases, including the baker's yeast Set3/Hos2 complex (Set3C), facilitate gene expression. In the dimorphic human ...

Author: Hnisz D.,Bardet A. F.,Nobile C. J.,Petryshyn A.,Glaser W.,Schock U.,Stark A.,Kuchler K.

Date Published: 14th Dec 2012

Journal: PLoS Genet

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