Reinhard Guthke
Bioprocess data analysis (data mining)
Transcriptomics and proteomics data analysis and modelling
Gene Regulatory Network inference (Reverse engineering)
Decision making support systems in diagnostics, therapy and biotechnology
SEEK ID: https://funginet.hki-jena.de/people/2
Location:
Germany
Disciplines: Modeller, Bioinformatician
Expertise: Integrative Data Analysis, Mathematical Modelling, Gene Regulatory Network Inference
ORCID: Not specified
Reinhard's tagsFungiNet total (Leibniz-Institute for Natural Product Research and Infection Biology Hans Knöll Institute (HKI)) ; FungiNet B - Bioinformatics projects (Leibniz-Institute for Natural Product Research and Infection Biology Hans Knöll Institute (HKI)) ; FungiNet A - Aspergillus projects (Leibniz-Institute for Natural Product Research and Infection Biology Hans Knöll Institute (HKI)) ; B3 (E) (Leibniz-Institute for Natural Product Research and Infection Biology Hans Knöll Institute (HKI)) ; FungiNet C - Candida projects (Leibniz-Institute for Natural Product Research and Infection Biology Hans Knöll Institute (HKI)) ; C5 (Leibniz-Institute for Natural Product Research and Infection Biology Hans Knöll Institute (HKI))
Related items
Gastrointestinal colonisation and mechanisms of translocation of Candida albicans through gut mucosa
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Primary hepatocytes were exposed to a stimulus by exchanging culture medium, thereby simulating changes in the blood composition. The expression of genes at different time points was recorded. Differentially expressed genes were clustered using fuzzy c-means algorithm into five groups. The arcs of the possible network were identified using the NetGenerator algorithm under the restriction of biological knowledge. The analysis was restricted to the main metabolic pathways of hepatocytes. The reverse
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Creators: Thomas Wolf, Wolfgang Schmidt-Heck, Reinhard Guthke
Contributor: Thomas Wolf
Model type: Ordinary differential equations (ODE)
Model format: SBML
Environment: JWS Online
RNA-Seq is a method to measure the transcript/gene expression by adaption of High-throughput sequencing technologies. In contrast to microarrays where the measurement is based on a hybridization process, RNA-Seq sequences cDNA in order to get information about a sample's RNA content.
Creators: Reinhard Guthke, Jörg Linde, Steffen Priebe
Contributor: Reinhard Guthke
Abstract (Expand)
Authors: Jörg Linde, Reinhard Guthke, Axel Brakhage, Vito Valiante, Horn F.,Mattern D. J.,Walther G.,Scherlach K.,Martin K.,Petzke L.
Date Published: 12th Mar 2016
Journal: Genome Announc
Abstract (Expand)
Authors: Jörg Linde, Reinhard Guthke, Priebe S.,Albrecht D.,Brakhage A. A.
Date Published: 10th Nov 2010
Journal: Fungal Genet Biol
Abstract (Expand)
Authors: Jörg Linde, Bernhard Hube, Reinhard Guthke, Tierney L.,Muller S.,Brunke S.,Molina J. C.,Schock U.,Kuchler K.
Date Published: 12th Mar 2012
Journal: Front Microbiol
Abstract (Expand)
Authors: Vito Valiante, Olaf Kniemeyer, Axel Brakhage, Monteiro M. C.,Martin J.,Altwasser R.,El Aouad N.,Gonzalez I.,Mellado E.,Palomo S.,de Pedro N.,Perez-Victoria I.,Tormo J. R.,Vicente F.,Reyes F.,Genilloud O.
Date Published: 8th Jun 2015
Journal: Antimicrob Agents Chemother
Abstract (Expand)
Authors: Jörg Linde, Sylvie Schulze, Reinhard Guthke, Henkel S. G.
Date Published: 2nd Mar 2015
Journal: EXCLI J
9. September 2014
A5 und B1
Slevogt / Schuster
Start Date: 9th Sep 2014
End Date: Not specified
Event Website: Not specified
Country: Germany
City: Jena
