Projects: Not specified
Institutions: Not specified
Projects: Not specified
Institutions: Not specified
Expertise: innate immunity, Candida albicans, fungal pathogens, Immune evasion
Tools: Microbiology, multicolour flow cytometry, Molecular Biology
I am a Phd student at the Institute for virology and Immunobiology, University of Wuerzburg.
Projects: FungiNet total, C2, FungiNet C - Candida projects
Institutions: Julius Maximilians University Würzburg, Institute for Molecular Infection Biology

Roles: Project Coordinator
Expertise: Candida albicans, Molecular Biology, Transcriptional Regulation
Tools: Genetic analysis, Molecular Biology
Project leader C2
Projects: FungiNet C - Candida projects, FungiNet total, C2
Institutions: Friedrich Schiller University Jena, Center for Innovation Competence (ZIK) Septomics
Roles: Project Coordinator
Expertise: Candida albicans, Transcriptional Regulation, metabolism, pathogenesis
Tools: Microscopy, Biochemistry and protein analysis, Molecular Biology, Cell biology
Projects: C2, FungiNet total, FungiNet C - Candida projects
Institutions: Friedrich-Schiller-University
Expertise: Candida albicans
Projects: B1, B2, FungiNet B - Bioinformatics projects, FungiNet total
Institutions: Julius Maximilians University Würzburg, Biocenter, Department of Bioinformatics
Roles: PhD Student
Expertise: Proteomics, Lichtheimia corymbifera, Data Management, protein-protein interaction, Integrative Data Analysis, Aspergillus fumigatus, Bioinformatics, Candida albicans, Host-Pathogen Interaction
Tools: Phosphoproteomics, Transcriptomics, R, JavaScript, Network analysis, Proteomics, MySQL, PHP, Python, Java
Projects: C2, FungiNet C - Candida projects, FungiNet total
Institutions: Julius Maximilians University Würzburg, Institute for Molecular Infection Biology
Roles: Postdoc
Expertise: Molecular Biology, Candida albicans, Protein Kinases
This model is a variant of the previously developed SBM of whole-blood infection assay. While in the previous model a spontaneous immune evasion mechanism (A) was implemented in this model immune evasion was caused by PMN molecule secretion (B).
Creators: Teresa Lehnert, Maria T. E. Prauße
Contributor: Sandra Timme
Model type: Not specified
Model format: Not specified
Environment: Not specified
Organism: Candida albicans
Investigations: No Investigations
Studies: No Studies
Modelling analyses: No Modelling analyses
The state-based model (SBM) allow to simulate the interplay between innate immune cells, such as monocytes and PMN, and Candida albicans and to quantify immune reaction rates like phagocytosis and killing rates. It is implemented in C++.
Creator: Teresa Lehnert
Contributor: Sandra Timme
Model type: Not specified
Model format: Not specified
Environment: Not specified
Organism: Candida albicans
Investigations: No Investigations
Studies: No Studies
Modelling analyses: No Modelling analyses
Abstract (Expand)
Authors: S. Du, C. Vilhena, S. King, A. Sahagun-Ruiz, S. Hammerschmidt, Christine Skerka, Peter Zipfel
Date Published: 18th Jan 2021
Journal: Sci Rep
PubMed ID: 33462258
Citation: Sci Rep. 2021 Jan 18;11(1):1701. doi: 10.1038/s41598-020-79362-3.
Abstract (Expand)
Authors: Luke Donald Halder, M. A. Abdelfatah, E. A. Jo, Ilse Jacobsen, M. Westermann, Niklas Beyersdorf, S. Lorkowski, Peter Zipfel, Christine Skerka
Date Published: 31st Jan 2017
Journal: Front Immunol
PubMed ID: 28133459
Citation: Front Immunol. 2017 Jan 13;7:671. doi: 10.3389/fimmu.2016.00671. eCollection 2016.
Abstract (Expand)
Authors: Sarah Irmscher, N. Doring, Luke Donald Halder, E. A. H. Jo, I. Kopka, C. Dunker, Ilse Jacobsen, S. Luo, Hortense Slevogt, S. Lorkowski, Niklas Beyersdorf, Peter Zipfel, Christine Skerka
Date Published: 14th Dec 2017
Journal: J Innate Immun
PubMed ID: 29237166
Citation: J Innate Immun. 2018;10(2):94-105. doi: 10.1159/000484257. Epub 2017 Dec 14.
Abstract (Expand)
Authors: Luke Donald Halder, E. A. H. Jo, M. Z. Hasan, M. Ferreira-Gomes, Thomas Krüger, M. Westermann, D. I. Palme, G. Rambach, Niklas Beyersdorf, C. Speth, Ilse Jacobsen, Olaf Kniemeyer, Berit Jungnickel, Peter Zipfel, Christine Skerka
Date Published: 11th May 2020
Journal: Nat Commun
PubMed ID: 32393780
Citation: Nat Commun. 2020 May 11;11(1):2331. doi: 10.1038/s41467-020-16241-5.
Abstract (Expand)
Authors: Esther Klaile, M. M. Muller, C. Zubiria-Barrera, S. Brehme, Tilman Klassert, M. Stock, A. Durotin, T. D. Nguyen, S. Feer, B. B. Singer, Peter Zipfel, Sven Rudolphi, Ilse Jacobsen, Hortense Slevogt
Date Published: 19th Dec 2019
Journal: Front Microbiol
PubMed ID: 31849868
Citation: Front Microbiol. 2019 Nov 26;10:2703. doi: 10.3389/fmicb.2019.02703. eCollection 2019.
Abstract (Expand)
Authors: Barbara Schaarschmidt, S. Vlaic, A. Medyukhina, S. Neugebauer, S. Nietzsche, F. A. Gonnert, J. Rodel, M. Singer, M. Kiehntopf, Marc Thilo Figge, Ilse Jacobsen, Michael Bauer, A. T. Press
Date Published: 8th Aug 2018
Journal: Theranostics
PubMed ID: 30083258
Citation: Theranostics. 2018 Jun 13;8(14):3766-3780. doi: 10.7150/thno.24333. eCollection 2018.
Abstract (Expand)
Authors: M. Maurer, M. S. Gresnigt, A. Last, T. Wollny, F. Berlinghof, R. Pospich, Z. Cseresnyes, A. Medyukhina, K. Graf, M. Groger, M. Raasch, F. Siwczak, S. Nietzsche, Ilse Jacobsen, Marc Thilo Figge, Bernhard Hube, O. Huber, A. S. Mosig
Date Published: 10th Aug 2019
Journal: Biomaterials
PubMed ID: 31398556
Citation: Biomaterials. 2019 Nov;220:119396. doi: 10.1016/j.biomaterials.2019.119396. Epub 2019 Aug 2.
Abstract (Expand)
Authors: B. Bottcher, B. Hoffmann, E. Garbe, T. Weise, Z. Cseresnyes, Philipp Brandt, Stefanie Dietrich, D. Driesch, Marc Thilo Figge, Slavena Vylkova
Date Published: 20th May 2020
Journal: Front Microbiol
PubMed ID: 32425915
Citation: Front Microbiol. 2020 Apr 30;11:794. doi: 10.3389/fmicb.2020.00794. eCollection 2020.
Abstract (Expand)
Authors: Stefanie Allert, Toni Förster, Carl-Magnus Svensson, J. P. Richardson, T. Pawlik, B. Hebecker, Sven Rudolphi, M. Juraschitz, M. Schaller, M. Blagojevic, Joachim Morschhäuser, Marc Thilo Figge, Ilse Jacobsen, J. R. Naglik, Lydia Kasper, Selene Mogavero, Bernhard Hube
Date Published: 5th Jun 2018
Journal: mBio
PubMed ID: 29871918
Citation: mBio. 2018 Jun 5;9(3). pii: mBio.00915-18. doi: 10.1128/mBio.00915-18.
Abstract (Expand)
Authors: N. Al-Zaben, A. Medyukhina, Stefanie Dietrich, A. Marolda, Kerstin Hünniger, Oliver Kurzai, Marc Thilo Figge
Date Published: 1st Mar 2019
Journal: Sci Rep
PubMed ID: 30824740
Citation: Sci Rep. 2019 Mar 1;9(1):3317. doi: 10.1038/s41598-019-39725-x.
Abstract (Expand)
Authors: A. Wartenberg, Jörg Linde, R. Martin, M. Schreiner, F. Horn, Ilse Jacobsen, S. Jenull, Thomas Wolf, K. Kuchler, Reinhard Guthke, Oliver Kurzai, A. Forche, C. d'Enfert, S. Brunke, Bernhard Hube
Date Published: 4th Dec 2014
Journal: PLoS Genet
PubMed ID: 25474009
Citation:
Abstract (Expand)
Authors: K. Czakai, I. Leonhardt, Andreas Dix, M. Bonin, Jörg Linde, Hermann Einsele, Oliver Kurzai, Jürgen Löffler
Date Published: 28th Jun 2016
Journal: Sci Rep
PubMed ID: 27346433
Citation: