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Strain details
Name | Provider name | Provider's strain ID | Genotypes | Phenotypes | Synonym | Comments | Based on |
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Related items
Impact of regulatory T cells on human infections caused by Aspergillus fumigatus
Image data analysis and agent-based modelling of the spatio-temporal interaction between immune cells and human-pathogenic fungi
Integrated database for experimental data
Within the Collaborative Research Center / Transregio 124 “Pathogenic fungi and their human host: Networks of Interaction – FungiNet”, the INF project is responsible to analyse and share OMICS data. Databases help to foster the collaboration within FungiNet as an important point of the Collaborative Research Center. Therefore, we set-up two databases:
a) SEEK is a web-based platform to find, share and exchange unstructured data and knowledge, such as
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Modelling interactions between the host and fungal pathogens by combining metabolic pathway analysis and evolutionary game theory
Adaptation of the previously developed virtual infection model of Aspergillus fumigatus in a *human* alveolus.
This model comprises a hybrid agent-based model of a single murine alveolus. The alveolus is represented in a realistic to-scale representation and contains the cell types of alveolar epithelial cells (AEC) of type 1 and 2 as well as the pores of Kohn (PoK).
Furthermore, in this model, depending on the infection dose multiple A. fumigatus conidium are inserted into the alveolus and the
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Creators: Sandra Timme, Marco Blickensdorf
Contributor: Sandra Timme
Model type: Agent based modelling
Model format: Not specified
Environment: Not specified
Organism: Aspergillus fumigatus
Investigations: No Investigations
Studies: No Studies
Modelling analyses: No Modelling analyses
This model comprises a hybrid agent-based model of a single human alveolus. The alveolus is represented in a realistic to-scale representation and contains the cell types of alveolar epithelial cells (AEC) of type 1 and 2 as well as the pores of Kohn (PoK). A single A. fumigatus conidium in inserted into the alveolus and the AEC, where the conidium is located secretes chemokines. Chemokine secretion is modelled using the partial differential equation of the diffusion equation and numerically
...
Creator: Johannes Pollmächer
Contributor: Sandra Timme
Model type: Agent based modelling
Model format: Not specified
Environment: Not specified
Organism: Aspergillus fumigatus
Investigations: No Investigations
Studies: No Studies
Modelling analyses: No Modelling analyses
This is the image analysis algorithm used in Cseresnyes, Kraibooj and Figge, Hessian-based quantitative image analysis of host-pathogen confrontation assays
Cytometry A. 2018 Mar;93(3):346-356. doi: 10.1002/cyto.a.23201. Code is being maintained at https://github.com/applied-systems-biology/ACAQ3.
Read.me
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This package contains code that implements the Hessian-based macrophage segmentation algorithm.
In addition, the
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Creator: Carl-Magnus Svensson
Contributor: Carl-Magnus Svensson
Model type: Not specified
Model format: Not specified
Environment: Not specified
Organism: Aspergillus fumigatus
Investigations: No Investigations
Studies: No Studies
Modelling analyses: No Modelling analyses
Abstract (Expand)
Authors: M. Blickensdorf, Sandra Timme, Marc Thilo Figge
Date Published: 27th Feb 2019
Journal: Front Immunol
PubMed ID: 30804941
Citation: Front Immunol. 2019 Feb 5;10:142. doi: 10.3389/fimmu.2019.00142. eCollection 2019.
Abstract (Expand)
Authors: Z. Cseresnyes, Kaswara Kraibooj, Marc Thilo Figge
Date Published: 16th Sep 2017
Journal: Cytometry A
PubMed ID: 28914994
Citation: Cytometry A. 2018 Mar;93(3):346-356. doi: 10.1002/cyto.a.23201. Epub 2017 Sep 15.
Abstract (Expand)
Authors: J. Pollmacher, Sandra Timme, Stefan Schuster, Axel Brakhage, Peter Zipfel, Marc Thilo Figge
Date Published: 13th Jun 2016
Journal: Sci Rep
PubMed ID: 27291424
Citation: Sci Rep. 2016 Jun 13;6:27807. doi: 10.1038/srep27807.
Abstract (Expand)
Authors: H. Irmer, S. Tarazona, C. Sasse, P. Olbermann, J. Loeffler, S. Krappmann, A. Conesa, G. H. Braus
Date Published: 28th Aug 2015
Journal: BMC Genomics
PubMed ID: 26311470
Citation: BMC Genomics. 2015 Aug 27;16:640. doi: 10.1186/s12864-015-1853-1.
Abstract (Expand)
Authors: J. Pollmacher, Marc Thilo Figge
Date Published: 16th Jun 2015
Journal: Front Microbiol
PubMed ID: 26074897
Citation: Front Microbiol. 2015 May 28;6:503. doi: 10.3389/fmicb.2015.00503. eCollection 2015.