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Submitter
Jan Ewald1
Project
B21
Creator
Jan Ewald1
Model type
Ordinary differential equations (ODE)1
Model format
Matlab package1
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Dynamic optimization model to study control points in metabolic pathways to identify general strategies behind pathway regulation. Toxic intermediates determine which enzyme control pathway flux and prevent their accumulation. Therefore those enzymes are drug targets since deregulation leads to self-poisoning of pathogens.