Mitochondrion

The yeast Candida albicans and the filamentous fungus Aspergillus fumigatus are by far the most important causes of life-threatening invasive mycoses in Europe. Despite the increasing incidence of these infections, the current diagnosis is still difficult and often too late, and options for therapies are limited. Moreover, A. fumigatus and C. albicans have developed multiple sophisticated, specific and unique pathogenicity mechanisms. Many of these mechanisms are not well understood. Research on ...

Integrated database for experimental data

Within the Collaborative Research Center / Transregio 124 “Pathogenic fungi and their human host: Networks of Interaction – FungiNet”, the INF project is responsible to analyse and share OMICS data. Databases help to foster the collaboration within FungiNet as an important point of the Collaborative Research Center. Therefore, we set-up two databases:

a) SEEK is a web-based platform to find, share and exchange unstructured data and knowledge, such as ...

In project Z2 a sophisticated proteome analysis platform will be provided based on 2D-gel electrophoresis (2D-GE), MALDI-TOF and LC-MS/MS techniques to specific A and Cprojects.

M Vödisch, D Albrecht, F Leßing, A D Schmidt, R Winkler, R Guthke, A A Brakhage, OKniemeyer. Two-dimensional proteome reference maps for the human-pathogenic filamentous fungus Aspergillus fumigatus. Proteomics. 2009 Mar;9(5):1407-1415. View

J Teutschbein, D Albrecht, M Pötsch, R Guthke, V Aimanianda, C Clavaud, JP Latge, A A Brakhage, O Kniemeyer. Proteome Profiling and Functional Classification of Intracellular Proteins from Conidia of the Human-Pathogenic Mold Aspergillus fumigatus. J Proteome ...