Projects

Interaction of Aspergillus fumigatus with human natural killer cells, dendritic cells and human alveolar epithelia

In vivo analysis of temporal and spatial disease progression and immune cell recruitment during invasive Aspergillus fumigatus and Candida albicans infections

Impact of regulatory T cells on human infections caused by Aspergillus fumigatus

Comparative analysis of the Dectin1-mediated immune response in Candida albicans and Aspergillus fumigatus infections and its regulation by nuclear receptors

Modelling interactions between the host and fungal pathogens by combining metabolic pathway analysis and evolutionary game theory

Interaction networks of signalling molecules and pathways between the pathogenic fungi Aspergillus fumigatus and Candida albicans and their human host

Predictive modelling of host-fungal pathogen interactions by reconstruction of gene regulatory networks

Image data analysis and agent-based modelling of the spatio-temporal interaction between immune cells and human-pathogenic fungi

Integrated database for experimental data

Within the Collaborative Research Center / Transregio 124 “Pathogenic fungi and their human host: Networks of Interaction – FungiNet”, the INF project is responsible to analyse and share OMICS data. Databases help to foster the collaboration within FungiNet as an important point of the Collaborative Research Center. Therefore, we set-up two databases:

a) SEEK is a web-based platform to find, share and exchange unstructured data and knowledge, such as
...

In project Z2 a sophisticated proteome analysis platform will be provided based on 2D-gel electrophoresis (2D-GE), MALDI-TOF and LC-MS/MS techniques to specific A and Cprojects.

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