Kroll K, Shekhova E, Mattern DJ, Thywissen A, Jacobsen ID, Strassburger M, Heinekamp T, Shelest E, Brakhage AA, Kniemeyer O. The hypoxia-induced dehydrogenase HorA is required for coenzyme Q10 biosynthesis, azole sensitivity and virulence of Aspergillus fumigatus. Mol Microbiol 2016 Mar 17. doi: 10.1111/mmi.13377
SEEK ID: https://funginet.hki-jena.de/investigations/60
Projects: Z2
Investigation position:
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Created: 29th Apr 2021 at 09:08

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Institutions: BioControl Jena GmbH
The yeast Candida albicans and the filamentous fungus Aspergillus fumigatus are by far the most important causes of life-threatening invasive mycoses in Europe. Despite the increasing incidence of these infections, the current diagnosis is still difficult and often too late, and options for therapies are limited. Moreover, A. fumigatus and C. albicans have developed multiple sophisticated, specific and unique pathogenicity mechanisms. Many of these mechanisms are not well understood. Research on ...
Projects: FungiNet total, FungiNet A - Aspergillus projects, FungiNet B - Bioinformatics projects, FungiNet C - Candida projects, INF, A1, A2, A3, A4 (E), A5, B1, B2, B3 (E), B4, C1, C2, C3, C4 (E), C5, C6 (E), Z2, Z1, B5, A6, A7, A8, C7
Web page: http://www.funginet.de/home.html
In project Z2 a sophisticated proteome analysis platform will be provided based on 2D-gel electrophoresis (2D-GE), MALDI-TOF and LC-MS/MS techniques to specific A and Cprojects.
pool of both samples
Submitter: Daniela Albrecht-Eckardt
Investigation: Proteom analysis of AFUA_4G09810 (Delta horA)
Assays: 2D gels
Snapshots: No snapshots
100 mL AMM were inoculated with 10E7 conidia and incubated at 37°C and 200 rpm until half of the avaiable glucose was consumed
Submitter: Daniela Albrecht-Eckardt
Investigation: Proteom analysis of AFUA_4G09810 (Delta horA)
Assays: 2D gels
Snapshots: No snapshots
100 mL AMM were inoculated with 10E7 conidia and incubated at 37°C and 200 rpm until half of the avaiable glucose was consumed
Submitter: Daniela Albrecht-Eckardt
Investigation: Proteom analysis of AFUA_4G09810 (Delta horA)
Assays: 2D gels
Snapshots: No snapshots
Submitter: Daniela Albrecht-Eckardt
Assay type: Experimental Assay Type
Technology type: Technology Type
Investigation: Proteom analysis of AFUA_4G09810 (Delta horA)
Study: Delta_4G09810
Submitter: Daniela Albrecht-Eckardt
Assay type: Experimental Assay Type
Technology type: Technology Type
Investigation: Proteom analysis of AFUA_4G09810 (Delta horA)
Study: wild type
Submitter: Daniela Albrecht-Eckardt
Assay type: Experimental Assay Type
Technology type: Technology Type
Investigation: Proteom analysis of AFUA_4G09810 (Delta horA)
Study: internal standard
Creator: Daniela Albrecht-Eckardt
Submitter: Daniela Albrecht-Eckardt
Investigations: Proteom analysis of AFUA_4G09810 (Delta horA)
Studies: Delta_4G09810
Assays: 2D gels
Creator: Daniela Albrecht-Eckardt
Submitter: Daniela Albrecht-Eckardt
Creator: Daniela Albrecht-Eckardt
Submitter: Daniela Albrecht-Eckardt
Investigations: Proteom analysis of AFUA_4G09810 (Delta horA)
Studies: internal standard
Assays: 2D gels