The term open reading frame (ORF) is of central importance to gene finding. Surprisingly, at least three definitions are in use. We discuss several molecular biological and bioinformatics aspects, and we recommend using the definition in which an ORF is bounded by stop codons.
PubMed ID: 29366605
Journal: Trends Genet
Citation: Trends Genet. 2018 Mar;34(3):167-170. doi: 10.1016/j.tig.2017.12.009. Epub 2018 Jan 30.
Date Published: 26th Jan 2018
Created: 20th Feb 2021 at 15:02