Projects: Not specified
Institutions: Not specified
Projects: B1, B2, FungiNet B - Bioinformatics projects, FungiNet total
Institutions: Julius Maximilians University Würzburg, Biocenter, Department of Bioinformatics
Roles: PhD Student
Expertise: Proteomics, Lichtheimia corymbifera, Data Management, protein-protein interaction, Integrative Data Analysis, Aspergillus fumigatus, Bioinformatics, Candida albicans, Host-Pathogen Interaction
Tools: Phosphoproteomics, Transcriptomics, R, JavaScript, Network analysis, Proteomics, MySQL, PHP, Python, Java
Projects: FungiNet A - Aspergillus projects, FungiNet total, A1
Institutions: Leibniz-Institute for Natural Product Research and Infection Biology Hans Knöll Institute (HKI)

Roles: Postdoc
Expertise: Molecular Biology, Host-Pathogen Interaction, Aspergillus fumigatus, Immune evasion, fungal pathogens, infection models
Tools: Molecular Biology, Mouse models
I study the analysis of high-throughput transcriptom and genome data.
For transcritom data (RNA-Seq, microarrays), I perform preprocessing and statistics to identify differentially expressed genes, as well as their functional analysis. My main focus is the analysis of transcriptom data
from human fungal pathogens in infection related conditions (f.e. nutrient limitation) as well as during the interaction with the host (dual RNA-seq).
Experimental data is used to set up mathematical models for
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Projects: C5, FungiNet C - Candida projects, FungiNet total
Institutions: Leibniz-Institute for Natural Product Research and Infection Biology Hans Knöll Institute (HKI)
Expertise: fungal pathogens, in vivio Imaging, Biochemistry, Host-Pathogen Interaction, infection models, Imaging, Molecular Biology
Tools: Bioluminescence Imaging, Laser-scanning-fluorescence microscopy, Multiparameter-Flowcytometry, Cytometry and fluorescent microscopy, Mouse models, Immunological techniques, Molecular Biology
Name
Prof. Dr. Thomas Dandekar
Position Professor and Chairman
Affiliation
Dept. of bioinformatics,
Biocenter
University of Würzburg
Am Hubland
97074 Würzburg
Phone 0931-318-4551
dandekar@biozentrum.uni-wuerzburg.de
Born 23.07.1960
Career 1979-1986 Studies in medicine at the Ludwig Maximilians University of Munich
1982-1986 MD, Max Planck Inst. of Psychiatry, Dept. Neuropharmacology, Martinsried
1987-1988 Post-Doc, Institute Pasteur, Paris
1988- now Scientist at the European Molecular Biology
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Projects: Not specified
Institutions: Not specified
The following bullet points characterise my scientific interests and research:
- Metabolic physiology of fungi during host infection
- Biochemical characterisation of metabolic pathways (enzyme purification and characterisation)
- Development of infection models
- Generation of fungal reporter strains
- In vivo imaging of the infection process
- Secondary metabolites from Aspergillus terreus (gene regulation, product formation, biological activity)