Abstract (Expand)

Invasive fungal infections are associated with high mortality rates and are mostly caused by the opportunistic fungi Aspergillus fumigatus and Candida albicans. Immune responses against these fungi are ...

Authors: Andreas Dix, Jörg Linde, Hermann Einsele, Oliver Kurzai, Jürgen Löffler, Czakai K.,Leonhardt I.,Bonin M.

Date Published: 28th Jun 2016

Journal: Sci Rep

Abstract (Expand)

As part of the innate immune system, natural killer (NK) cells are directly involved in the response to fungal infections. Perforin has been identified as the major effector molecule acting against ...

Authors: Dragana Slavkovic Lukic, Jürgen Löffler, Daniela Albrecht-Eckardt, Michael Weber, Stefanie Allert, Oliver Kurzai, Kerstin Hünniger, Voigt J.,Bouzani M.,Martin R.

Date Published: 19th May 2016

Journal: Front Microbiol

Abstract (Expand)

Invasive aspergillosis (IA) is a devastating opportunistic infection and its treatment constitutes a considerable burden for the health care system. Immunocompromised patients are at an increased risk ...

Authors: Andreas Dix, Reinhard Guthke, Hermann Einsele, Jörg Linde, Jürgen Löffler, Czakai K.,Springer J.,Fliesser M.,Bonin M.,Schmitt A. L.

Date Published: 21st Mar 2016

Journal: Front Microbiol

Abstract (Expand)

Aspergillus fumigatus is the species that most commonly causes the opportunistic infection invasive aspergillosis (IA) in patients being treated for hematological malignancies. Little is known about ...

Authors: Jürgen Löffler, Hermann Einsele, Reinhard Guthke, Axel Brakhage, Olaf Kniemeyer, Teutschbein J.,Simon S.,Lother J.,Springer J.,Hortschansky P.,Morton C. O.,Conneally E.,Rogers T. R.

Date Published: 15th Mar 2016

Journal: J Proteome Res

Abstract (Expand)

BACKGROUND: Natural killer (NK) cells are innate lymphocytes with potent cytotoxic activity. Whereas activity of NK cells has been demonstrated against the fungal pathogens Aspergillus fumigatus and ...

Authors: Kerstin Hünniger, Ilse Jacobsen, Bernhard Hube, Jürgen Löffler, Oliver Kurzai, Voigt J.,Bouzani M.,Barz D.

Date Published: 25th Oct 2013

Journal: J Infect Dis

Abstract (Expand)

Aspergillus fumigatus is a common airborne fungal pathogen of humans and a significant source of mortality in immunocompromised individuals. Here, we provide the most extensive cell wall proteome ...

Authors: Thorsten Heinekamp, Thomas Krüger, Esther Weiß, Kerstin Hünniger, Jürgen Löffler, Oliver Kurzai, Hermann Einsele, Olaf Kniemeyer, Axel Brakhage, Voltersen V.,Blango M. G.,Herrmann S.,Schmidt F.,Strassburger M.,Bacher P.,Lother J.,Liu H.,Hortschansky P.,Scheffold A.,Krappmann S.,Nietzsche S.,Filler S. G.,Reichard U.

Date Published: No date defined

Journal: MBio

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