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Kruppel-like Factor 4 modulates interleukin-6 release in human dendritic cells after in vitro stimulation with Aspergillus fumigatus and Candida albicans

FungiNet A - Aspergillus projects, FungiNet B - Bioinformatics projects, FungiNet C - Candida projects, INF

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Abstract (Expand)

Invasive fungal infections are associated with high mortality rates and are mostly caused by the opportunistic fungi Aspergillus fumigatus and Candida albicans. Immune responses against these fungi are ...

Authors: Andreas Dix, Jörg Linde, Hermann Einsele, Oliver Kurzai, Jürgen Löffler, Czakai K.,Leonhardt I.,Bonin M.

Date Published: 28th Jun 2016

Journal: Sci Rep

PubMed ID: 27346433

Citation:

Created: 8th Jul 2016 at 07:13

Candida albicans Induces Metabolic Reprogramming in Human NK Cells and Responds to Perforin with a Zinc Depletion Response

FungiNet A - Aspergillus projects, FungiNet C - Candida projects

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Abstract (Expand)

As part of the innate immune system, natural killer (NK) cells are directly involved in the response to fungal infections. Perforin has been identified as the major effector molecule acting against ...

Authors: Dragana Slavkovic Lukic, Jürgen Löffler, Daniela Albrecht-Eckardt, Michael Weber, Stefanie Allert, Oliver Kurzai, Kerstin Hünniger, Voigt J.,Bouzani M.,Martin R.

Date Published: 19th May 2016

Journal: Front Microbiol

PubMed ID: 27242763

Citation:

Created: 8th Jul 2016 at 07:39

Genome-Wide Expression Profiling Reveals S100B as Biomarker for Invasive Aspergillosis

FungiNet A - Aspergillus projects, FungiNet B - Bioinformatics projects, INF, B3 (E)

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Abstract (Expand)

Invasive aspergillosis (IA) is a devastating opportunistic infection and its treatment constitutes a considerable burden for the health care system. Immunocompromised patients are at an increased risk ...

Authors: Andreas Dix, Reinhard Guthke, Hermann Einsele, Jörg Linde, Jürgen Löffler, Czakai K.,Springer J.,Fliesser M.,Bonin M.,Schmitt A. L.

Date Published: 21st Mar 2016

Journal: Front Microbiol

PubMed ID: 27047454

Citation:

Created: 29th Apr 2016 at 11:39

Proteomic Profiling of Serological Responses to Aspergillus fumigatus Antigens in Patients with Invasive Aspergillosis

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Abstract (Expand)

Aspergillus fumigatus is the species that most commonly causes the opportunistic infection invasive aspergillosis (IA) in patients being treated for hematological malignancies. Little is known about ...

Authors: Jürgen Löffler, Hermann Einsele, Reinhard Guthke, Axel Brakhage, Olaf Kniemeyer, Teutschbein J.,Simon S.,Lother J.,Springer J.,Hortschansky P.,Morton C. O.,Conneally E.,Rogers T. R.

Date Published: 15th Mar 2016

Journal: J Proteome Res

PubMed ID: 26974881

Citation:

Created: 28th Apr 2016 at 15:42

Human natural killer cells acting as phagocytes against Candida albicans and mounting an inflammatory response that modulates neutrophil antifungal activity

FungiNet A - Aspergillus projects, FungiNet C - Candida projects

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Abstract (Expand)

BACKGROUND: Natural killer (NK) cells are innate lymphocytes with potent cytotoxic activity. Whereas activity of NK cells has been demonstrated against the fungal pathogens Aspergillus fumigatus and ...

Authors: Kerstin Hünniger, Ilse Jacobsen, Bernhard Hube, Jürgen Löffler, Oliver Kurzai, Voigt J.,Bouzani M.,Barz D.

Date Published: 25th Oct 2013

Journal: J Infect Dis

PubMed ID: 24163416

Citation:

Created: 8th Mar 2016 at 09:10

Proteome Analysis Reveals the Conidial Surface Protein CcpA Essential for Virulence of the Pathogenic Fungus Aspergillus fumigatus.

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Abstract (Expand)

Aspergillus fumigatus is a common airborne fungal pathogen of humans and a significant source of mortality in immunocompromised individuals. Here, we provide the most extensive cell wall proteome ...

Authors: Thorsten Heinekamp, Thomas Krüger, Esther Weiß, Kerstin Hünniger, Jürgen Löffler, Oliver Kurzai, Hermann Einsele, Olaf Kniemeyer, Axel Brakhage, Voltersen V.,Blango M. G.,Herrmann S.,Schmidt F.,Strassburger M.,Bacher P.,Lother J.,Liu H.,Hortschansky P.,Scheffold A.,Krappmann S.,Nietzsche S.,Filler S. G.,Reichard U.

Date Published: No date defined

Journal: MBio

PubMed ID: 30279286

Citation: MBio. 2018 Oct 2;9(5). pii: mBio.01557-18. doi: 10.1128/mBio.01557-18.

Created: 15th Jan 2019 at 12:50