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FungiNet total4
FungiNet A - Aspergillus projects4
A32
FungiNet B - Bioinformatics projects1
FungiNet C - Candida projects1
INF1
A21
A81
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Institution
Julius Maximilians University Würzburg, Department of Internal Medicine II2
Julius Maximilians University Würzburg, Rudolf Virchow Center, DFG Research Center for Experimental Biomedicine2
Leibniz-Institute for Natural Product Research and Infection Biology Hans Knöll Institute (HKI)1
Location
Germany4
6
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Projects: Not specified
Institutions: Not specified
The following bullet points characterise my scientific interests and research:
- Metabolic physiology of fungi during host infection
- Biochemical characterisation of metabolic pathways (enzyme purification and characterisation)
- Development of infection models
- Generation of fungal reporter strains
- In vivo imaging of the infection process
- Secondary metabolites from Aspergillus terreus (gene regulation, product formation, biological activity)
I study the analysis of high-throughput transcriptom and genome data.
For transcritom data (RNA-Seq, microarrays), I perform preprocessing and statistics to identify differentially expressed genes, as well as their functional analysis. My main focus is the analysis of transcriptom data from human fungal pathogens in infection related conditions (f.e. nutrient limitation) as well as during the interaction with the host (dual RNA-seq). Experimental data is used to set up mathematical models for ...