DynaCoSys models the complement system by using a combination of Ordinary and Partial Differential Equations.

Creators: Teresa Lehnert, Alexander Tille

Contributor: Sandra Timme

Primary hepatocytes were exposed to a stimulus by exchanging culture medium, thereby simulating changes in the blood composition. The expression of genes at different time points was recorded. Differentially expressed genes were clustered using fuzzy c-means algorithm into five groups. The arcs of the possible network were identified using the NetGenerator algorithm under the restriction of biological knowledge. The analysis was restricted to the main metabolic pathways of hepatocytes. The reverse

Creators: Thomas Wolf, Wolfgang Schmidt-Heck, Reinhard Guthke

Contributor: Thomas Wolf

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