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modelling5
Ordinary differential equations3
Partial differential equations3
alveolus2
Aspergillus fumigatus2
Candida albicans2
lung2
monocytes2
neutrophils2
state-based model2
Systems Biology2
agent-based model1
alveolar epithelial cells1
alveolar macrophages1
antibody-antigen binding1
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complement regulator factor H1
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computational biology1
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hybrid differential equation approach1
ImageJ1
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mouse1
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pathway regulation1
Python1
receptor-ligand interaction1
virtual infection model1
whole-blood assay1
whole-blood infection assay1
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Creator
Teresa Lehnert4
Carl-Magnus Svensson3
Reinhard Guthke1
Wolfgang Schmidt-Heck1
Sandra Timme1
Thomas Wolf1
Jan Ewald1
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Model type
Agent based modelling3
Ordinary differential equations (ODE)3
Partial differential equations (PDE)1
Recommended environment
JWS Online1
11
Models visible to you, out of a total of 23
Dynamic optimization model to study control points in metabolic pathways to identify general strategies behind pathway regulation. Toxic intermediates determine which enzyme control pathway flux and prevent their accumulation. Therefore those enzymes are drug targets since deregulation leads to self-poisoning of pathogens.