Adaptation of the previously developed virtual infection model of Aspergillus fumigatus in a *human* alveolus.
This model comprises a hybrid agent-based model of a single murine alveolus. The alveolus is represented in a realistic to-scale representation and contains the cell types of alveolar epithelial cells (AEC) of type 1 and 2 as well as the pores of Kohn (PoK).
Furthermore, in this model, depending on the infection dose multiple A. fumigatus conidium are inserted into the alveolus and the
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Creators: Sandra Timme, Marco Blickensdorf
Contributor: Sandra Timme
Model type: Agent based modelling
Model format: Not specified
Environment: Not specified
Organism: Aspergillus fumigatus
Investigations: No Investigations
Studies: No Studies
Modelling analyses: No Modelling analyses
Abstract (Expand)
Authors: J. Pollmacher, Marc Thilo Figge
Date Published: 16th Jun 2015
Journal: Front Microbiol
PubMed ID: 26074897
Citation: Front Microbiol. 2015 May 28;6:503. doi: 10.3389/fmicb.2015.00503. eCollection 2015.
Abstract (Expand)
Authors: Teresa Lehnert, Marc Thilo Figge
Date Published: 19th Dec 2017
Journal: Front Immunol
PubMed ID: 29250071
Citation: Front Immunol. 2017 Nov 30;8:1692. doi: 10.3389/fimmu.2017.01692. eCollection 2017.