2 items tagged with 'pathway regulation'.
Dynamic optimization model to study control points in metabolic pathways to identify general strategies behind pathway regulation.
Toxic intermediates determine which enzyme control pathway flux and prevent their accumulation.
Therefore those enzymes are drug targets since deregulation leads to self-poisoning of pathogens.
Creator: Jan Ewald
Contributor: Jan Ewald
Model type: Ordinary differential equations (ODE)
Model format: Matlab package
Environment: Not specified
Organism: Not specified
Investigations: No Investigations
Studies: No Studies
Modelling analyses: No Modelling analyses
Created: 24th Aug 2017 at 08:34
Dynamic optimization of pathway regulation and intermediate toxicity prediction to elucidate drug targets in pathogenic fungi
Created: 24th Aug 2017 at 08:44