Projects

Cross talk of Aspergillus fumigatus with neutrophilic granulocytes

Interaction of Aspergillus fumigatus with human natural killer cells, dendritic cells and human alveolar epithelia

In vivo analysis of temporal and spatial disease progression and immune cell recruitment during invasive Aspergillus fumigatus and Candida albicans infections

Impact of regulatory T cells on human infections caused by Aspergillus fumigatus

Immunomodulatory functions of ITAM- and ITIM-coupled receptors (C-type lectins/CTLs and carcinoembryonic antigen-related cell adhesion molecules/CEACAMs) for C. albicans -induced immune responses

Surface proteins of Lichtheimia corymbifera as virulence determinants

Predictive modelling of host-fungal pathogen interactions by reconstruction of gene regulatory networks

Molecular mycology, fungal/host interactions, pathogenicity mechanisms of Candida albicans

Regulation of Candida albicans virulence traits by protein kinases

Intrinsic modulation of neutrophil antifungal activity against Candida albicans

Mechanisms of adhesion and modulation of human immune cells by Candida albicans

Gastrointestinal colonisation and mechanisms of translocation of Candida albicans through gut mucosa

Role of secreted Candida albicans proteins in immune evasion and pathogenicity

Integrated database for experimental data

Within the Collaborative Research Center / Transregio 124 “Pathogenic fungi and their human host: Networks of Interaction – FungiNet”, the INF project is responsible to analyse and share OMICS data. Databases help to foster the collaboration within FungiNet as an important point of the Collaborative Research Center. Therefore, we set-up two databases:

a) SEEK is a web-based platform to find, share and exchange unstructured data and knowledge, such as
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